brand name : ATUBRI 500MG TABLET

Generic name : Capecitabine

Basic Info

Use of Drug

Colorectal cancer

Breast cancer 

Gastric cancer

Oesophageal cancer

Category Of Drug

Anticancer Drugs

Side Effects

Gastrointestinal Disorders - Diarrhea, nausea, mouth ulcer, vomiting, abdominal pain, gastrointestinal hemorrhage constipation, upper abdominal pain and indigestion.

Skin - Hand Foot Syndrome, hair loss, rash and redness.

General - Injection site pain, irritation, swelling, fatigue, fever, chest pain, back pain, weakness and lethargy

Central Nervous System - Dizziness, depression, sleep disorders, headache and abnormal taste.

Metabolic - Loss of appetite.

Eye - Eye inflammation and loss of vision.

Blood - Decreased white blood cells.

Respiratory - Nosebleed, cough and sore throat.

Drug Dose Information

Oral
Breast cancer:

Adult: 
1.25 g/m2 bid for 2 wk followed by a 1 wk rest period; therapy to be given in 3-wk cycles. 
Recommended treatment duration for colorectal cancer: 6 mth. May be used in combination with docetaxel at 75 mg/m2, given as a 1-hr IV infusion once every 3 wk for the treatment of breast cancer.

Oral
Colorectal cancer:

Adult: 1.25 g/m2 bid for 2 wk followed by a 1 wk rest period; therapy to be given in 3-wk cycles. Recommended treatment duration for colorectal cancer: 6 mth. 
May be used in combination with docetaxel at 75 mg/m2, given as a 1-hr IV infusion once every 3 wk for the treatment of breast cancer.

Oral
Gastric cancer:

Adult: Used in combination with a platinum-based compound, 1 g/m2 bid for 14 days, followed by a 7-day rest period. 1st dose is given on the evening of day 1 and the last dose on the morning of day 15.

Precautions

Hepatic dysfunction
Bone marrow suppression
Poor nutritional status
Warfarin therapy
Child, elderly, prior extensive pelvic radiation or alkylating therapy
Moderate renal impairment
CBC with differential
Monitor hepatic and renal function
Discontinue use if intractable diarrhoea
Stomatitis
Bone marrow suppression or MI develops

Brand Information

Brand Name	ATUBRI 500MG TABLET
Contains	Capecitabine 500 mg
Manufacturer Name	Pfizer Limited

Brand Specifications
	Unit	Quantity	Price	Type
1	3 ml	1	93.0000	Eye drops

How To Take

It is available as a tablet taken orally, with food, two times per day.

History of severe and unexpected reactions to fluoropyrimidine therapy Severe renal impairment Pregnancy Lactation Hypersensitivity Kidney problems or dihydropyrimidine dehydrogenase (DPD) enzyme deficiency and hypersensitivity.

Diseases

Hypertension : .

Glaucoma : Glaucoma is a term describing a group of ocular disorders with multi-factorial etiology united by a clinically characteristic intraocular pressure-associated optic neuropathy. Treatment 1Balance and postural control 2Medications • Prostaglandin analogs, latanoprost ,bimatoprost and travoprost . • Topical beta-adrenergic receptor antagonists, such as timolol, levobunolol and betaxolol. • Alpha2-adrenergic agonists, such as brimonidine and apraclonidine. • Less-selective alpha agonists, such as epinephrine. • Miotic agents (parasympathomimetics), such as pilocarpine.Echothiophate, an acetylcholinesterase inhibitor, is used in chronic glaucoma. • Carbonic anhydrase inhibitors, such as dorzolamide , brinzolamide ,and acetazolamide . • Physostigmine

Interactions

Fosphenytoin Leucovorin Levoleucovorin Phenytoin Varicella Virus Vaccine Warfarin Yellow Fever Vaccine Adenovirus Vaccine Type 4, Live Adenovirus Vaccine Type 7, Live Bacillus of Calmette and Guerin Vaccine, Live Influenza Virus Vaccine, Live Measles Virus Vaccine, Live Mumps Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Vaccine Typhoid Vaccine

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drug’s Side effects

It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

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brand name : ATUBRI 500MG TABLET

Generic name : Capecitabine

Basic Info

Use of Drug

Category Of Drug

Side Effects

Drug Dose Information

Precautions

Brand Information

How To Take

Storage

Contra Indications

Diseases

Interactions

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brand name : ATUBRI 500MG TABLET

Generic name : Capecitabine

Basic Info

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drug’s Side effects

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