CLOFRANIL SR 75MG
Clomipramine 75 mg
Sun Pharmaceuticals Industries Limite
It is available as a tablet and capsule taken orally, with food.
Store protected from light and moisture.
Recent myocardial infarction Arrhythmias Manic phase in bipolar disorders Severe liver disease Children Porphyria Narrow angle glaucoma Urinary retention
Alzheimer's disease : Alzheimer's disease is a neurological disorder in which the death of brain cells causes memory loss and cognitive decline. A neurodegenerative type of dementia, the disease starts mild and gets progressively worse. And it is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death. Drugs has too little role in the management of Alzheimer’s disease No medication has been clearly shown to delay or halt the progression of the disease. Drugs used are • Acetylcholinesterase inhibitors – Donepezil, Galantamine, Rivastigmine • NMDA-receptor (N-Methyl-D-aspartate receptor) antagonist -Memantine Dementia : Dementia is a serious loss of global cognitive ability in a previously unimpaired person, beyond what might be expected from normal aging. Cholinesterase inhibitors (donepezil)are often used early in the disease course; however, benefit is slight. Cognitive and behavioral interventions may also be appropriate. Educating and providing emotional support to the caregiver is of importance as well elderly care. Exercise programs are beneficial with respect to activities of daily living and potentially improve
Linezolid or MAOIs (eg, phenelzine) because the risk of high blood pressure, serious heart problems (eg, irregular heartbeat), or seizures may be increased. Barbiturates (eg, phenobarbital) or phenytoin because they may decrease clomipramine's effectiveness. Anticholinergics (eg, benztropine), anticoagulants (eg, warfarin), carbamazepine, digoxin, or sympathomimetics (eg, phenylephrine) because the risk of their side effects may be increased by clomipramine. Clonidine, guanethidine, or guanfacine because their effectiveness may be decreased by clomipramine.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.