Cabre
CABERGOLINE
Inga Laboratories Pvt. Ltd
Should be taken with food.
Oral: Store at 20-25°C.
Hypersensitivity to ergot derivatives Uncontrolled hypertension
Heartburn : Heartburn is a painful burning feeling just below or behind the breastbone. Most of the time it comes from the esophagus. The pain often rises in your chest from your stomach and may spread to your neck or throat. Almost everyone has heartburn sometimes. If you have heartburn very often, you may have gastroesophageal reflux disease (GERD). Normally when food or liquid enters your stomach, a band of muscle at the end of your esophagus closes off the esophagus. This band is called the lower esophageal sphincter (LES). If this band does not close tightly enough, food or stomach acid can back up (reflux) into the esophagus. The stomach contents can irritate the esophagus and cause heartburn and other symptoms. Pregnancy and many medications can bring on heartburn or make it worse. Medication Antacids may be taken after meals, at bedtime, or when needed, to bind excess acid in the stomach and to coat the esophagus. Histamine H2 antagonists are medications that block the action of histamine (a chemical that stimulates stomach cells to produce acid) on the acid-producing cells of the stomach. This decreases acid production to hopefully decrease symptoms. Examples include: • cimetidine (Tagamet), • ranitidine (Zantac), and • famotidine (Pepcid). Proton pump inhibitors (PPIs) are another class of drugs that block the production of acid by the stomach. PPIs include: • omeprazole (Prilosec, Rapinex), • rabeprazole (Aciphex) • pantoprazole (Protonix) • lansoprazole (Prevacid), and • esomeprazole (Nexium).
Dopamine antagonists such as the phenothiazines, butyrophenones,thioxanthenes, and metoclopramide might be expected to reduce the prolactin lowering and the antiparkinsonian effects of cabergolin and domperidone might reduce its prolactin lowering effect. Memantine may enhance the effects of cabergolin. Stimulants of gastrointestinal motility such as macrolide antibacterials or octreotide can increase the bioavailability of cabergolin. Alcohol intolerance was noted in 5 of 73 patients receiving cabergolin 10 to 60 mg daily for the treatment of acromegaly. Two patients who had gastrointestinal adverse effects while taking low doses of cabergolin had a marked reduction in their symptoms and were able to tolerate higher doses when they refrained completely from alcohol. Antibacterials Drowsiness, dystonia, choreoathetoid dyskinesias,and visual hallucinations occurred when josamycin was given to a patient receiving cabergolin. Antifungals
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.