DICLOFENAC SODIUM INJECTION
Diclofenac
Cadila Pharmaceuticals Limited
Diclofenac is available as a tablet, and liquid-filled capsule, a hard gelatin capsule, an extended-release (long-acting) tablet, a delayed-release (releases medication in the intestine) tablet, and as packets of powder for solution (to be mixed with water) and taken orally. Take tabllets or capsules with meals, milk, or antacids to minimize GI distress. Diclofenac liquid-filled capsules are usually taken 4 times a day and diclofenac hard gelatin capsules are usually taken three times a day on an empty stomach.
Store it at room temperature and away from excess heat and moisture.
Active peptic ulcer Hypersensitivity to diclofenac or other NSAIDs Treatment of perioperative pain in CABG surgery 3rd trimester of pregnancy Topical: Not to be applied onto damaged or non-intact skin
Hypotension (Low Blood Pressure) : Hypotension, also referred to as Low Blood Pressure. Low blood pressure occurs when blood pressure is much lower than normal. This means the heart, brain, and other parts of the body do not get enough blood. Normal blood pressure is usually between 90/60 mmHg and 130/80 mmHg. Certain medicines and substances can lead to low blood pressure, including: • Alcohol • Anti-anxiety medicines • Certain antidepressants • Diuretics • Heart medicines, including those used to treat high blood pressure and coronary heart disease • Medicines used for surgery • Painkillers Other causes of low blood pressure include: • Nerve damage from diabetes • Changes in heart rhythm (arrhythmias) • Not drinking enough fluids (dehydration) • Heart failure Symptoms Symptoms of low blood pressure may include: • Blurry vision • Confusion • Dizziness • Fainting (syncope) • Lightheadedness • Nausea or vomiting • Sleepiness • Weakness Treatment • Use more salt. • Drink more water. Fluids increase blood volume and help prevent dehydration, both of which are important in treating hypotension. • Wear compression stockings. The same elastic stockings commonly used to relieve the pain and swelling of varicose veins may help reduce the pooling of blood in your legs. • Medications. Several medications, either used alone or together, can be used to treat low blood pressure that occurs when you stand up (orthostatic hypotension). The drug fludrocortisone is often used to treat this form of low blood pressure.
Not to be given IV to patients who are receiving other NSAIDs or anticoagulants including low dose heparin. Renal function may be worsened when used with ciclosporin or triamterene. Altered absorption when given with sucralfate, colestyramine or colestipol. Ophthalmic application of diclofenac may reduce the efficacy of ophthalmic acetylcholine and carbachol. Increased risk of GI ulceration and bleeding when used with corticosteroids, aspirin or anticoagulants. Potentially fatal: Increases blood levels of digoxin, lithium and methotrexate. Potentiate potassium-sparing diuretics.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.