Darilong
DARIFENACIN
Sun Pharmaceuticals Industries Limite
Darifenacin can be taken with or without food.
Store it at room temperature (25°C). Protect from light
Patient with urinary retention Gastric retention Uncontrolled narrow-angle glaucoma
Rickets : .Osteomalacia : .Osteoporosis : Osteoporosis causes bones to become weak and brittle — so brittle that a fall or even mild stresses like bending over or coughing can cause a fracture. Osteoporosis-related fractures most commonly occur in the hip, wrist or spine. Bone is living tissue, which is constantly being absorbed and replaced. Osteoporosis occurs when the creation of new bone doesn't keep up with the removal of old bone. Symptoms Signs and symptoms include: • Back pain, caused by a fractured or collapsed vertebra • Loss of height over time • A stooped posture • A bone fracture that occurs much more easily than expected Treatments For both men and women, the most widely prescribed osteoporosis medications are bisphosphonates. Examples include: • Alendronate (Fosamax, Binosto) • Risedronate (Actonel, Atelvia) • Ibandronate (Boniva) • Zoledronic acid (Reclast, Zometa)
Concurrent use of CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, clarithromycin, nefazodone, troleandomycin, ritonavir, nelfinavir) or CYP2D6 inhibitors (e.g. quinidine, paroxetine) may increase serum levels of Darifenacin. CYP3A4 inducers (e.g. barbiturates, phenytoin, rifampicin) may likely decrease Darifenacin serum concentrations. Darifenacin may act as a moderate inhibitor of CYP2D6, caution when used concomitantly with CYP2D6 substrates that have narrow therapeutic index (e.g. flecainide, thioridazine, imipramine). Concurrent use of another agent with antimuscarinic properties may potentiate the side effects of Darifenacin.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.