OBIMET GX
Glimepiride,Metformin Hydrochloride
Abbott India
It is available as a tablet taken orally, with food.
Store protected from light and moisture.
Renal impairment (withdraw if renal impairment suspected withdraw if tissue hypoxia likely (for example sepsis, respiratory failure, recent myocardial infarction, hepatic impairment) Use of iodine-containing X-ray contrast media (do not restart metformin until renal function returns to normal) and use of general anaesthesia (suspend metformin 2 days beforehand and restart when renal function returns to normal) Alcohol dependence Pregnancy Anaemia Ketosis
Osteoporosis : Osteoporosis causes bones to become weak and brittle — so brittle that a fall or even mild stresses like bending over or coughing can cause a fracture. Osteoporosis-related fractures most commonly occur in the hip, wrist or spine. Bone is living tissue, which is constantly being absorbed and replaced. Osteoporosis occurs when the creation of new bone doesn't keep up with the removal of old bone. Symptoms Signs and symptoms include: • Back pain, caused by a fractured or collapsed vertebra • Loss of height over time • A stooped posture • A bone fracture that occurs much more easily than expected Treatments For both men and women, the most widely prescribed osteoporosis medications are bisphosphonates. Examples include: • Alendronate (Fosamax, Binosto) • Risedronate (Actonel, Atelvia) • Ibandronate (Boniva) • Zoledronic acid (Reclast, Zometa)
Additive effect with sulphonylureas. Glycaemic control may be affected by diuretics, corticosteroids, phenothiazines, thyroid products, oestrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, chlorpromazine and isoniazid. Metformin effects may be increased by ACE inhibitors, disopyramide, MAOIs. Cimetidine may increase the serum levels of metformin. Concurrent use with contrast agents may increase the risk of metformin-induced lactic acidosis. May decrease the anticoagulant effect of phenprocoumon, therefore routine anticoagulant monitoring is recommended. Potentially fatal: Lactic acidosis with alcohol. Thrombocytopenia has been reported with ketotifen.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.