ROGLIMET 2MG/2MG/500MG TABLET
Glimepiride 2 mg,Metformin 2 mg,Rosiglitazone 500 mg
Wockhardt Health Care Ltd.
It is available as a tablet taken orally, with food
Store protected from moisture at temperature not exceeding 30°C.
Hypersensitivity Pregnancy Diabetic ketoacidosis
Graves' disease : Graves' disease (or Basedow-Graves disease) is an autoimmune disease. It most commonly affects the thyroid, frequently causing it to enlarge to twice its size or more (goiter), become overactive, with related hyperthyroid symptoms such as increased heartbeat, muscle weakness, disturbed sleep, and irritability. Treatment of Graves' disease includes antithyroid drugs which reduce the production of thyroid hormone; radioiodine (radioactive iodine I-131); and thyroidectomy (surgical excision of the gland) Hyperthyroidism : Hyperthyroidism is a condition in which an overactive thyroid gland is producing an excessive amount ofthyroid hormones that circulate in the blood. ("Hyper" means "over" in Greek). Thyrotoxicosis is a toxic condition that is caused by an excess of thyroid hormones from any cause. Thyrotoxicosis can be caused by an excessive intake of thyroid hormone or by overproduction of thyroid hormones by the thyroid gland. TREATMENT Treatment depends on the cause and the severity of symptoms. Hyperthyroidism is usually treated with one or more of the following: • Antithyroid medications • Radioactive iodine to destroy the thyroid gland and stops the excess production of hormones • Surgery to remove the thyroid Medicines called beta-blockers may be prescribed to treat symptoms such as fast heart rate, sweating, and anxiety until the hyperthyroidism can be controlled.
NSAIDs, salicylates, sulphonamides, chloramphenicol, coumarin, probenecid, CYP2C9 inhibitors, fibric acid derivatives, pegvisomant, TCAs, MAOIs and ß-adrenergic blockers may potentiate the hypoglycaemic action of glimepiride. Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, oestrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, rifampicin, CYP2C9 inducers and isoniazid may reduce hypoglycaemic effect of glimepiride. May increase the serum levels of ciclosporin. Serum levels may be increased by fluconazole.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.