TRAMAZAC-PD
tramadol hydrochloride , acetaminophen , domperidone .
Zydus Cadila (Alidac Division)
It available as a tablet, capsule taken orally with or without food. It is available as a solution for injection to be administered by a healthcare provider into the vein or large muscle.
Store it at room temperature (25°C).
Patients with suicidal tendency Raised intracranial pressure Severe renal impairment Acute alcoholism Lactation
Hypertension : .Glaucoma : Glaucoma is a term describing a group of ocular disorders with multi-factorial etiology united by a clinically characteristic intraocular pressure-associated optic neuropathy. Treatment 1Balance and postural control 2Medications • Prostaglandin analogs, latanoprost ,bimatoprost and travoprost . • Topical beta-adrenergic receptor antagonists, such as timolol, levobunolol and betaxolol. • Alpha2-adrenergic agonists, such as brimonidine and apraclonidine. • Less-selective alpha agonists, such as epinephrine. • Miotic agents (parasympathomimetics), such as pilocarpine.Echothiophate, an acetylcholinesterase inhibitor, is used in chronic glaucoma. • Carbonic anhydrase inhibitors, such as dorzolamide , brinzolamide ,and acetazolamide . • Physostigmine
Alcohol (Ethanol) Moderate Drug Interaction Reduced analgesic efficacy of tramadol with carbamezapine,5-HT3 receptor antagonist eg:Ondansetron Possible increase in anticoagulation with warfarin Antidepressants SSRI: increased risk of CNS toxicity when tramadol given with SSRIs. Antidepressants Tricyclic: increased risk of CNS toxicity when tramadol given with tricyclics Coumarins: tramadol enhances anticoagulant effect of coumarins Seligiline: caution with tramadol advised by manufacturer of selegiline.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.