NUFLAM RB 200MG/20MG CAPSULE SR
Aceclofenac200 mg,Rabeprazole20 mg
Cadila Pharmaceuticals Limited
It comes as a tablet to take by mouth, with food.
Store it in an airtight container in a cool dry place. Protect from light
In patients with severe ulcer Gastrointestinal bleeding Hypersensitivity
Ulcerative colitis : Ulcerative colitis is a chronic inflammation of the large intestine (colon). The colon is the part of the digestive system where water is removed from undigested material, and the remaining waste material is stored. The rectum is the end of the colon adjacent to the anus. In patients with ulcerative colitis, ulcers and inflammation of the inner lining of the colon lead to symptoms of abdominal pain, diarrhea, and rectal bleeding. Common symptoms of ulcerative colitis include rectal bleeding, abdominal pain, and diarrhea, but there is a wide range of symptoms among patients with this disease. Variability of symptoms reflects differences in the extent of disease (the amount of the colon and rectum that are inflamed) and the intensity of inflammation. Generally, patients with inflammation confined to the rectum and a short segment of the colon adjacent to the rectum have milder symptoms and a better prognosis than patients with more widespread inflammation of the colon. Medication Medications treating ulcerative colitis include 1) anti-inflammatory agents such as 5-ASA compounds, systemic corticosteroids, topical corticosteroids, and 2) immunomodulators. Anti-inflammatory medications that decrease intestinal inflammation are analogous to arthritis medications that decrease joint inflammation (arthritis). The anti-inflammatory medications that are used in the treatment of ulcerative colitis are: • Topical 5-ASA compounds such as sulfasalazine (Azulfidine),olsalazine (Dipentum), and mesalamine (Pentasa, Asacol, Lialda, Apriso Rowasa enema) that need direct contact with the inflamed tissue in order to be effective. • Systemic anti-inflammatory medications such as corticosteroids that decrease inflammation throughout the body without direct contact with the inflamed tissue. Systemic corticosteroids have predictable side effects with long term use. • immunomodulators include 6-mercaptopurine (6-MP), azathioprine (Imuran), methotrexate (Rheumatrex, Trexall), cyclosporine (Gengraf, Neoral).
Increased risk of renal impairment when Aceclofenac given with ACE inhibitors (perindopril ,captopril, enalapril, lisinopril and ramipril ), Angiotensin - II receptor antagonists ( Losartan, candesartan , telmisartan and Valsartan ), Ciclosporin,Tacrolimus and Diuretics. Antagonise hypotensive effect with ACE inhibitors, Adrenergic neurone blockers,Alphablockers, Angiotensin -II receptor antagonists, Betablockers, Calcium channel blockers, clonidine, Diazoxide, Hydralazine, Methyl dopa, Minoxidine, Moxonidine, Nitrates and Nitroprusside. Increased risk of bleeding with Antidepressants, Clopidrogel, Erlotinib, Iloprost, Pentoxifylline Sibutramine and Venlafaxine. Aceclofenac probably reduce excretion of lithium (increased risk of toxicity). Possible increased risk of convulsions when Aceclofenac given with quinolones.
Whether you're looking for a doctor for dealing with your own medical condition, click here to find right physician.
It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.